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Dec 26, 2021 - Python
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Screen antibody, TCR, and peptide sequences for developability liabilities — the motifs that cause deamidation, isomerization, fragmentation, unwanted glycosylation, oxidation, and cysteine problems.
Local-first PySide6 antibody research workbench for sequence liability screening, batch analysis, literature evidence, and optional ESM2-based ML estimates.
Reproducible antibody developability workflow combining sequence and structure indicators with cautious viscosity analysis on published datasets.
Identifying potential liabilities in therapeutic antibody candidates using 3D structure analysis. Takes a protein structure in PDB format through preprocessing and liability detection to flag developability risks.
Local antibody developability screening, structure modeling, and substitution prioritization for resource-limited labs.
PhD project Github repository
Compute physicochemical properties (charge, GRAVY, pI, MW, ε) for peptide and antibody/TCR lead ranking
To associate your repository with the developability topic, visit your repo's landing page and select "manage topics."